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altering its production may affect downstream pathways in ways not yet studied long-term
The differential equations for the variables listed in Table1 are: Absorption and dosing APAP is absorbed from the gut into the portal circulation which flows into the liver
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Given the relatively smaller reduction in body weight (9.4%) in the SELECT trial compared to previous RCTs: 14.9% in STEP1 (BMI 37.86.7 kg/m 2 ) [16] and 13.2% STEP6 (BMI 31.9 kg/m 2 ) [49], pleiotropic effects of semaglutide may contribute to the overall CV risk reduction [25,37]
