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Its sensitivity can be modulated by the ambient substrate of the cell [124]
Neuroprotective effects of the novel brain-penetrating pyrrolopyrimidine antioxidants U-101033E and U-104067F against post-ischemic degeneration of nigrostriatal neurons
To maintain the dynamic equilibrium of the mitochondrial proteome, cells have evolved a sophisticated mitochondrial protein quality control (PQC) system that counters multiple stressors including aberrant polypeptide import, protein misfolding, oxidative damage, and metabolic byproduct accumulation [5,6,7]
J Psychiatr Ment Health Nurs 15:424434 Tardiolo G, Bramanti P, Mazzon E (2018) Overview on the effects of N-Acetylcysteine in neurodegenerative diseases