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As the direct reaction species to react with Si-based agent is hydroxide ions, the higher the pH of the reaction solution, the greater the amount of hydrogen generated from Si-based agent

doi: 10.1186/s12865-016-0187-3 16 XiaoHWCuiMLiYDongJLZhangSQZhuCCet al

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10.1038/bjc.1982.211 Br J Cancer

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pCS induce increased production of ROS, increased expression of NADPH oxidase, and increased expression of pro-inflammatory factors MCP-1 and TNF- in human endothelial cells and aortic smooth muscle (84)