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PT-141 (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH) is a cyclic, lactam-bridged analog of -melanocyte-stimulating hormone (-MSH) originally developed as a tanning peptide

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For musculoskeletal use, it is commonly considered for tendon irritation, ligament sprains, muscle strains, fascia-related pain, overuse injuries, and joint-adjacent soft-tissue pain

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