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Histamine intolerance supplements Vitamin C supplementation has also been shown to reduce histamine levels (ref), while B6 supplementation is also beneficial as it acts as a co-factor in DAO production (ref)

Some studies also point to its role in supporting brain-derived neurotrophic factor, a protein that helps neurons survive and form new connections

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primary applications The three ingredients are thought to work better together than alone, but formal studies testing this combination are still limited

therefore, the number of participants representing efficacy findings may differ from the number representing safety findings due to different pools of study participants analyzed for efficacy and safety