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Its unexplored and anecdotal in the context of GLP-1 drugs, but some patients report a general decrease in interest, pleasure and excitement in activities they previously enjoyed like eating out or socializing, he noted

Metabolic effects may persist slightly longer, up to 8 weeks post-discontinuation

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2022;34(1):59-74.e10

Notably, GLP-1R deletion in primary mouse astrocytes results in subtle mitochondrial dysfunction accompanied by a compensatory enhancement of glucose transporter-1-mediated aerobic glycolysis [22]

What Does This Mean for How People Actually Experience Stopping