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Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function

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The pentapeptide structure is relatively stable in lyophilized form but degrades more rapidly once in solution

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Important Note: Pregnant or breastfeeding women, individuals with medical conditions or those taking prescribed medications should consult a qualified healthcare professional before starting collagen supplementation

Walker RF, Bercu BB (1998) Comparative effects of GHRH and GHRP2