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NORMAN SWAN: The TGA's chief medical advisor is Professor Robyn Langham

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Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy

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It has been shown to lead to decreased cognitive decline among younger patients, albeit without improvements across all age groups, and will undergo a phase-3 clinical trial.ACI-35 immunotherapy has been used to target S-396/404 tau phosphorylation by generating specific antibodies, showing reduced soluble and insoluble tau in the brain and improving survival in animal-model studies (Theunis et al., 2013)