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But the real story is far more nuanced than most TikTok videos would have you believe

doi: 10.1186/s12912-020-00462-6

GLP-1RAs aid in weight loss by regulating the gut-brain axis and interacting with leptin, while weight loss can alleviate the harmful effects of obesity on the body, particularly in knee OA, by reducing joint loading and inflammation

These usually improve over time, but simple strategies can make them easier to manage