Compounding the problem is the fact that insurance companies are reluctant to cover these anti-obesity medications, since theyre considered by many to be vanity drugs, even though overwhelming evidence suggests obesity is linked directly to multiple comorbidities
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In this systematic review, the authors conducted a comprehensive analysis of clinical trials to determine the impact of GLP-1 receptor agonists in reducing substance use disorder in patients
Strategies such as hydration, smaller meals, adjusting fiber intake based on symptoms, and avoiding high-fat foods can ease symptoms
These symptoms often improve over time with continued use in most patients, and NPs can reduce discontinuation by starting at a low dose and titrating gradually
These trials used longer-acting GLP-1 receptor agonists, Gloyn said, which may help counter GLP-1 resistance
