Both lack human trials
Synaptogenesis in Precursor Analog Work (Clean, But Not Dihexa-Specific) Some of the synaptogenesis framing predates Dihexa and rests on cleaner work
Small bites every so often can make a big difference
Dosage: Take GLP-1 Probiotic Pro (has Akkermansia) daily Results: Clinical effects typically emerge within 13 months Pair the GLP-1 Probiotic Pro (2 capsules/day) to maximize Akkermansia growth
However, it must be stated that any possible beneficial liver effects of both SGLT2 inhibitors and GLP-1R agonists beyond weight loss are awaiting definitive proof in future mechanistic clinical studies [141, 142]
Cell Biochem Funct 21:5560 Zoroglu SS, Armutcu F, Ozen S, Gurel A, Sivasli E, Yetkin O, Meram I (2004) Increased oxidative stress and altered activities of erythrocyte free radical scavenging enzymes in autism