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Clinicians should address underlying motivations and provide evidence-based counseling

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While branded products undergo the full FDA approval process with Phase I through Phase III clinical trials, compounded versions operate under a different regulatory framework

This rising prevalence - influenced by aging populations, sedentary lifestyles, and increasing obesity rates - ensures sustained demand for improved therapies and intervention strategies

doi: 10.1136/bmjopen-2015-009686 51 HygumKHarslofTJorgensenNRRungbyJPedersenSBLangdahlBL