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Phase 3: optimized combination (week 11 onward) At this point the combination is running smoothly and the focus shifts to optimization and sustainability

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10.1039/c7fo01035d 113 WuJ.ChenM.ShiS.WangH.LiN.SuJ.et al (2017b)

The presence of severe nonproliferative DR or proliferative DR requires comanagement with retinology and further intervention, including intravitreal injection and/or laser photocoagulation consistent with the clinical standard of care

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