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The S-protein harbors an FCS between the S 1 /S 2 subunits, processed during biogenesis that sets this novel viral pathogen apart from other SARS-related CoVs 71

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PMID 24912947

The cardio-renal protection could be explained by both the reduction of glycemia, blood pressure, and weight, and through direct protective mechanisms (improved endothelial dysfunction, inflammation, and oxidative stress) of GLP-1 RAs on target organs [19]

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This aligns with our findings in the IIRI + LM mice model, in which Lactobacillus murinus treatment attenuated ferroptosis to preserve the intestinal barrier, further confirming the key role of Lactobacillus murinus in counteracting IIRI