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Internal support (nutrition): Provide collagen-building nutrients Delivers antioxidants Supports cellular hydration from within External support (skincare): Targets visible skin concerns Strengthens the skin barrier Protects against environmental exposure When you care for your skin from both directions, the benefits last longer

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To this end, we transiently transfected HEK-293T cells with vectors encoding full-length wild type SnCE1 and truncated SnCE1 74-310 with a C-terminal myc-His 6 -tag and performed subcellular fractionation to reveal to which cellular compartments SnCE1 localizes and whether the autoproteolytic processing modulated by the SnCE1 acetylation state affects the localization of SnCE1