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doi: 10.1007/s00018-005-5121-4

Maintenance : Sometimes 1 injection every 24 weeks

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Nausea or Upset Stomach: Some people may experience gastrointestinal discomfort, such as nausea, vomiting, or diarrhea, although these side effects are rare

We note that, for purposes of identifying significant procedure codes for examination under the 2 times rule, we consider procedure codes that have more than 1,000 single major claims or procedure codes that both have more than 99 single major claims and contribute at least 2 percent of the single major claims used to establish the APC cost to be significant (75 FR 71832)

Based on the CY 2024 claims data available for the CY 2026 OPPS/ASC proposed rule, we found 26 APCs with violations of the 2 times rule