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In contrast, active targeting involves the use of specific ligands, antibodies, or other molecules on the surface of nanocarriers to bind to receptors or antigens that are uniquely expressed, or overexpressed, on target cells, allowing for precise delivery [66]
In a phase 2 clinical trial, retatrutide reduced HbA1c to 2.02%, compared to 1.41% for dulaglutide 1.5 mg and 0.01% for placebo (Table 1)
Diabetes care 27 (11), 26282635
Levels of 17B-estradiol receptors expressed in embryonic and adult zebrafish following in vivo treatment of natural or synthetic ligands
Not everyone will see the same effects