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2010: FDA initially approved tesamorelin for reduction of excess abdominal fat in HIV-infected adults with lipodystrophy

You might have seen advertisements for the medication online, but make no mistake: Retatrutide has not been approved by the FDA and is not expected to receive approval before 2027

In addition, APOE4 is correlated with increased risk for atherosclerosis and amyloid plaque formation (165, 166)