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In 2023, sales of Mounjaro reached $5.163 billion, a 970% increase, far surpassing the initial performance of semaglutide, which had sales of $286 million in 2018 and $1.686 billion in 2019, a 490% increase

Its incidence is relatively high, especially in the early stages of medication, and some patients may experience mild to moderate nausea due to the high sensitivity of the gastrointestinal tract to drugs

doi: 10.1007/s11060-020-03483-y 84 Lee-ChangCRashidiAMiskaJZhangPPituchKCHouDet al

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Frag 176-191 retains only the lipolytic arm with no IGF-1 elevation, eliminating the major class-level side-effect concerns (gigantism, insulin resistance, certain tumor risk signals)

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