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June 24, 2024

Certain anti-obesity drugs, including selective serotonin reuptake inhibitors and naltrexone/bupropion combinations, have been linked to adverse psychological outcomes such as mood alterations and suicidal ideation [69]

& Glockner, J

A clinical study involving 564 adults (BMI 30-40 kg/m2, without T2DM) found that compared with orlistat (3120 mg, weight loss of 4.1 kg), LIR (subcutaneous administration of 1.2 mg/d, 1.8 mg/d, 2.4 mg/d or 3 mg/d) had an average weight loss of 4.8-7.2 kg, the two-year extended experiment of which also showed similar results (88, 89)

Energy-assisted fat reduction and muscle-building devices: Technologies like HIFEM+ cause thousands of muscle contractions in a session, increasing muscle mass while shrinking nearby fat

In comparison, lizard GLP-1 itself shares an 83% sequence identity to human GLP-1 (84) [ Figure 2 ]