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HepG2 cells were treated with 5 mol/ml (Figure 1A) and 10 mol/ml (Figure 1B) of ASA for 48 h and GSH levels in the mitochondria and post mitochondrial supernatant (PMS) were measured by enzymatic method as described in the Materials and Methods

Causes and risk factors Most cases of hyperactive thyroid disease are caused by an autoimmune response, meaning the bodys immune system mistakenly attacks thyroid tissue

& Grayer, R

Regulation of gamma-glutamylcysteine synthetase by nonallosteric feedback inhibition by glutathione

Evidence Gaps: Most positive findings come from topical formulations or small studies

doi:10.1128/AAC.00414-16 87