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It must be converted through multiple slow steps before your body can use it, and it accumulates in the blood as unmetabolized folic acid (UMFA). Methylfolate and folinic acid are the two active forms your body actually uses

The results you will see will change more than your body

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Stress management is another key factor

Without interchangeability, substitution requires active physician decision-making, which slows uptake considerably

Turck D, Bohn T, Castenmiller J, de Henauw S, Hirsch-Ernst KI, Knutsen HK et al (2023) Scientific opinion on the tolerable upper intake level for selenium