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Supervision is non-negotiable: tesamorelin requires a prescription, baseline labs, and ongoing monitoring for IGF-1 levels, glucose tolerance, and injection site reactions

Inter-individual Variation in Hepatic Drug Metabolism

Wilson CG, Tran JL, Erion DM, Vera NB, Febbraio M, Weiss EJ (2016) Hepatocyte-specific disruption of CD36 attenuates fatty liver and improves insulin sensitivity in HFD-fed mice

Why Im cautious: The human efficacy story is not in the same league as GLP-1 evidence

preserves physiologic feedback loops (somatostatin/IGF1 negative feedback)

the Yunnan Provincial High-level Scientific and Technological Talents and Innovative Teams Selection Special Project (Grant No