Other evidence also suggests that GLP-1R in the cerebral cortex affects hedonic feeding by targeting areas involved in reward and addiction (110)
Indeed, a search at (as of, Sep 14), employing cardiovascular disease and GLP-1 as keywords, returns 112 records comprising 42% completed, 39% recruiting, 8% not yet recruiting, 6% active, but not yet recruiting, 4% terminated, and 1% withdraw studies
Notably, weight loss continued throughout the trial period, with no plateau observed
SGLT-2, sodium-dependent glucose transporter-2
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Increased government focus on diabetes management programs and rising investments from global pharma players are accelerating adoption in the region