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Absolute contraindications include personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN 2)

Patients struggling with stubborn fat in the abdomen or hips often seek treatments that address liver efficiency

Weakness in the leg and knee joint, making activities that need the knee to bear weight or move difficult

Special Scenarios Post-COVID generalized weakness Documentation must be separate: active infection vs post-infectious recovery Objective strength deficits functional impairment and safety concerns structured plan with measured progress Weakness in older adults Older patients require clear separation between: generalized weakness (M62.81) confirmed sarcopenia (M62.84) Neurologic causes of weakness when present Fall risk documentation strengthens medical necessity when accurate and specific

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Friques et al., 2015)