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In Arabidopsis, arGST loss-of-function mutations were additionally linked with an increased content of flavonols 19,45 , most probably due to a second oxidation of accumulating flavan-3,3,4-triol ( 4 ), which is catalysed by At LDOX in vitro 11,12,13
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The version without DAC (sometimes called MOD-GRF(1-29)) has a much shorter half-life closer to standard GHRH, requiring more frequent dosing
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Some preclinical data suggests BPC-157 demonstrates oral bioavailability, but direct comparisons between oral and injectable delivery in humans have not been established through published clinical trials
doi: 10.1016/j.reprotox.2013.07.017 97 ANSES (French Agency for Food EaOHS
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