For example, deferiprone (DFP) and PBT2 have been shown to increase endothelial tight junction protein expression in AD models, reduce vascular leakage, and improve BBB integrity, suggesting an indirect BBB-protective potential (Ayton et al., 2025)
Alpha Arbutin works effectively to reduce the appearance of dark spots and pigmentation, while Niacinamide supports skin barrier function and enhances overall skin clarity
Understanding 5 Amino-1MQ: 5 Amino-1MQ is a novel molecule thats turning heads due to its role in inhibiting the enzyme NNMT (Nicotinamide N-methyltransferase)
Chung, B ., Choi, S., Moon, I., Park, C., Kim, Y.-H
Arch Biochem Biophys 191(1):153160 Flannigan KL, Agbor TA, Blackler RW, Kim JJ, Khan WI, Verdu EF, Ferraz JGP, Wallace JL (2014) Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis
(August 2011)