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Researchers have reported that MOTS-c treatment prevented the development of heart failure in a mouse model, an effect attributed to AMPK activation in the heart muscle and improvements in mitochondrial function

Some treatments, such as radiation or certain chemotherapies, rely on oxidative stress to work, and supplemental antioxidants could potentially interfere with those mechanisms

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In particular, microbial exposure has been shown to mitigate stress-induced behaviors and modulate immune responses, reinforcing the potential of microbial interventions in managing stress-related conditions (Lyte et al., 1998)