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In the case of epilepsy, impaired K + buffering, glutamate clearance, lipid accumulation and malfunctioning of the glutamate (GABA)-glutamine shuttle emerge as leading pathophysiological processes

Moreover, the lack of interaction with key residues, such as W297 and R380 involved in agonist potency hampers the global effectiveness of neuromedin C as a full GLP1R agonist

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The Role of Glutathione in the Body Antioxidant Defense : Glutathione neutralizes free radicals, reducing oxidative damage to cells