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4c), confirming protease-dependent cytokine release

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Unreported Symptoms While the population the researchers studied is admittedly not representative Reddit users are younger, more likely to be male and disproportionately based in the United States the symptoms described in their collective accounts largely match the known side effects of semaglutide and tirzepatide: about 44% of users in the study described at least one side effect, most commonly some form of gastrointestinal distress