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Because TB-500 reaches all tissues rather than concentrating at one site, the dosing strategy focuses on sustaining a systemic therapeutic level across the cycle rather than targeting a precise anatomical location

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In situ reduction of phospholipid and cholesterol hydroperoxides

Extended outages (4 to 24 hours) After 4 hours, interior temperatures begin rising above the safe zone

Pauling, PharmD, BCACP, is clinical associate professor and assistant dean for academic affairs at Binghamton University School of Pharmacy and Pharmaceutical Sciences

Modifications can be made to the termini of existing CPPs or the peptide backbone can be adjusted, such as through peptide cyclization, to improve stability and cell permeability