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However, past pancreatitis is not a contraindication for these agents, and contrary to the previous warning, recent studies have not shown an increased pancreatic risk associated with GLP-1 RAs, leading to ongoing revisions in treatment guidelines

The GLP-1 gum option is also a nice alternative medication modality for those patients who might not be interested in injections

Participants in RCTs typically comprise relatively healthy individuals, excluding those with a history of medullary thyroid cancer or pancreatitis, and the duration of the RCTs is insufficient to induce cancer

They were the first in class approved for the management of overweight and obesity, says Rothberg

FDA-Approved and Proven These aren't experimental or off-label treatments