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Wei L, Lu J, Xu H, et al

Exosome mediated multidrug resistance in cancer

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This is achieved, in part, by modulating the expression of pro-angiogenic factors such as Vascular Endothelial Growth Factor (VEGF) and Fibroblast Growth Factor 2 (FGF-2)

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Key Takeaway: GHK-Cu acts through multiple overlapping mechanisms fibroblast activation, controlled copper delivery, antioxidant signaling, and broad gene-expression modulation