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Major challenges in hydrogel-based delivery systems include difficulties with large-scale production, difficulties in precisely controlling gelation, the risk of immunogenicity, and the possibility of uneven drug distribution and retention within brain tissues

The kits should be stored in several places, such as in the bedroom or in a purse, a desk, a briefcase, or a backpack, and those individuals around the patient should know where the kits are located

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Rezano A, Khairinnisa A, Ekawardhani S