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Gene sequencing of mice revealed a significant upregulation of ferroptosis-related genes, indicating that the inhibition of tumor growth in vivo was associated with cell death caused by ESA in vitro (Beatty et al., 2021)

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Tirzepatide the active molecule in both Zepbound and Mounjaromimics these hormones to help regulate blood sugar and reduce appetite

doi: 10.1016/j.obmed.2020.100312 15 KubaKImaiYRaoSJiangCPenningerJM

Moreover, ferroptosis inhibitors can block NEDD4L-induced KGN cell death, suggesting that NEDD4L regulates ferroptosis in KGN cells (166)

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