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Heartburn specifically affected roughly 15% of patients, indicating it is a frequent side effect whose severity often rises with higher doses or overlapping risk factors

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Subsequent studies have revealed that the dose of lugdunin needed to prevent bacterial growth is comparable to that of the common antibiotic drugs

doi: 10.1038/s41440-018-0118-1

A large-scale analysis of Reddit, TikTok, and YouTube posts specifically identified sleep and insomnia as one of the key concerns users reported when discussing their experiences with these medications

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