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While purely speculative at this stage, the hypothesis warrants preclinical and translational investigation

Vitamin C's antioxidant qualities help lessen inflammation and delay the ageing process of the skin

If glycaemic control deteriorates despite good adherence, your clinician may investigate alternative causes including antibody development

Fontes-Carvalho R, Fontes-Oliveira M, Sampaio F, Mancio J, Bettencourt N, Teixeira M et al (2014) Influence of epicardial and visceral fat on left ventricular diastolic and systolic functions in patients after myocardial infarction

Certain surgical procedures