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A reliance on animal experiments may be misleading, given the substantial changes, not only in UA metabolism but also in its transport, associated with primate evolution 62

MerrillJTWallaceDJWaxSKaoAFraserPAChangPet al

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Hematoxylin and eosin staining The specimens were fixed using gradient ethanol solution, sequentially immersed for dehydration, cleared in xylene, and finally embedded in paraffin

Boissinot M, Vilaine M, Hermouet S