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Once you open a pen or vial, keep it in the refrigerator even between doses

Thats why new users are encouraged to start with one capsule for a few days before moving to the full dosage

Last reviewed: May 12, 2026 Last updated: May 12, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

The commissioners ultimately approved the cut by a narrow 10-7 vote

Health conditions or other factors that might interact with Januvia include: Heart failure: If you have heart failure or risk factors for it, talk with your doctor before taking Januvia

After 24 weeks, mean decreases from baseline of -2.9% for A1C, -127 mg/dL for FPG, and -208 mg/dL for 2-hour PPG were observed