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Published July 18, 2025
903 In a RANKL-induced osteoclast model, the bisphosphonate zoledronic acid promotes ferroptosis by increasing Fe 2+ , ROS, and MDA levels, and decreasing GPX4 and GSH levels
There is also the potential for use in neurodegenerative diseases, wherein oxidative stress plays a key role, though current evidence is not conclusive and more research is needed to establish efficacy in this regard