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GLP-1 activation slows gastric emptying, which reduces hunger but can also cause that uncomfortable food sitting in your stomach feeling

GLP-1 receptor agonists shift macrophage polarization toward the M2 phenotype

In a Phase 2 clinical trial , adults with overweight or obesity taking the lowest dose (1 mg) lost about 8.7% of their body weight on average after 48 weeks

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Siskind, Adam, et al

If youre newer to prescribing or supporting GLP-1 therapy, Ive put together a four-part series covering key considerations, including initiation, weight management, cost, and side effect mitigation