We don't expect our patients to become 100% keto, or paleo, or any of the extremes
The main representative drug of it is tirzepatide [135], which is a representative dual agonist commonly studied
Further studies are also needed in humans to determine whether APOE also influences L-carnitine metabolism following challenge and whether this impacts GBB and/or TMAO levels
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By promoting significant weight loss and potentially improving neuromuscular control of the airway, GLP-1 receptor agonists reduce the physical and physiological contributors to OSA, improving breathing during sleep
So unless you include regular exercise as part of your weight loss program, the weight you lose while taking Ozempic, Wegovy, Mounjaro or Zepbound will include both muscle and fat, but the weight you will regain after stopping the GLP-1 will be mostly fat, leaving you metabolically even worse off than when you started
