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389 GLP-1RAs and fat metabolism GLP-1RAs work via numerous mechanisms that contribute to weight loss, one of the most well-known of which is the gut-brain axis

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O estudo clnico fase II "Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes", publicado em junho de 2023 no The Lancet, avaliou a eficcia e a segurana da medicao em 281 pacientes com diabetes tipo 2 e sobrepeso ou obesidade durante 36 semanas de tratamento

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Some side effects are known and documented