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Meaning less cellular energy production and impaired mitochondrial function

Very small individuals (under 50kg) might start at the lower end of dose ranges

For patients without absorption disorders, high-dose oral B12 supplements (1,000-2,000 mcg daily) have been shown to be comparably effective to injections in correcting mild to moderate deficiency

However, in CY 2024, we finalized a policy to reduce the target PCR by 1.0 percentage point each calendar year ( until the target PCR equals the PCR of non-cancer hospitals using the most recently submitted or settled cost report data

This is typically temporary and resolves on its own

The 1:1 reflects "neither dominates." Reason 3: Practical reconstitution and dosing arithmetic