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The analysis also flagged reproductive symptoms, such as menstrual irregularities, and temperature-related complaints, such as chills and hot flashes, as possible GLP-1 side effects that deserve more research

Whether its Mounjaro, Zepbound, or another GLP-1, these drugs require medical supervision and should only be used under proper healthcare guidance

What Id genuinely like to see, and what the field needs, is a properly conducted Phase III randomised controlled trial in fibromyalgia patients, ideally with a sub-group of people with hypermobility and EDS, using low to moderate doses and with muscle mass, GI function, and bone health as pre-specified safety endpoints

Compare mechanism, peer-reviewed efficacy, dosing, side-effect profiles, and real Thai-clinic cost

Going in with that expectation set will make the experience more predictable regardless of the outcome

(NCBI) That distinction matters