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Shewale JB, Mitchell KG, Nelson DB, Conley AP, Rice DC, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG , Roth JA, Mehran RJ, Vaporciyan AA, Weissferdt A, Sepesi B

NavarroA.BoverisA.2007The mitochondrial energy transduction system and the aging process.2926706860363-6119 41

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Interestingly, PHGDH also affects tumor biology independently of its effects in serine metabolism, for example, directly interacting with the RNA-binding protein Poly(rC)-binding protein 2 (PCBP2), and inhibiting its proteasomal degradation