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Application Area Suggested Dosage Frequency Injury Recovery (muscle, tendon, ligament) 0.75 mg 1 mg Daily Joint & Tendon Inflammation 0.5 mg 0.75 mg Daily Gut Healing / GI Repair 0.25 mg 0.5 mg Daily Post-Surgical Recovery 1 mg Daily General Regeneration / Anti-inflammatory 0.5 mg 0.75 mg Daily or 5x per week

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CLOCK and BMAL1 the positive transcriptional activators in the core circadian loop have been shown to regulate DNA damage response pathways and to interact directly with telomere-binding proteins