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doi: 10.3389/fphar.2025.1667517 Received 16 July 2025 Accepted 29 August 2025 Published 10 September 2025 Volume 16 - 2025 Edited by Karl Tsim, Hong Kong University of Science and Technology, Hong Kong SAR, China Reviewed by Anglina Kisku, Dehradun Institute of Technology University, India Rahul Pal, Chitkara University, India Natalia Menshutina, D

Participants with renal impairment were recruited before those with normal renal function to help ensure similarity across groups in age and body weight