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Thyroxine therapy in patients with severe nonthyroidal illnesses and low serum thyroxine concentration

A truly remarkable study was published by Sherlock and associates in 2012 (discussed in Etiology ), the results of which were well summarized in a figure by Lories and McInnes ( Figure 4 - 10 ) that demonstrated that an excess of IL-23 is sufficient in generating specific prototypic SpA manifestations because mice injected with IL-23 genetic mini-circles (to overexpress IL-23) develop enthesitis and subsequently arthritis (including sacroiliitis), osteoproliferation, psoriasis and inflammation of the aortic root

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GLP-1 medications reduce the metabolic friction that keeps patients stuck

Reactions were initiated by the addition of 2 mM NADH