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Frias, J.P., Deenadayalan, S., Erichsen, L., Knop, F.K., Lingvay, I., Macura, S., Mathieu, C., Pedersen, S.D., & Davies, M.J

In elaboration of these observations, work in an alpha-cell-specific PC1/3 knockout mouse model demonstrates that the loss of alpha-cell GLP-1 production impairs glucose homeostasis and GSIS in metabolically stressed mice but not in chow-fed mice (19)

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